Cherubism: A Variant Case

Introduction: Cherubism, a form of osteolytic genetic disorder presents in childhood and tends to regress spontaneously after puberty. It is characterized by painless expansion of mandible or maxilla or both. Case Report: On radiography, the lesions exhibit bilateral multinuclear radiolucent areas. Histopathology reveals multinucleated giant cells in the background of proliferating fibrous connective tissue. Children are normal at birth and jaw is noticed to be expanding within the first few years of life progressing to further enlargement until adolescence. It is genetically inherited, although non familial cases have also been reported. The present case report describes a variant case of cherubism in 11year old male child with bilateral facial swelling and protruding mass over his gums. Conclusion: Cherubism is a rare osseous disorder found in children and adolescents. Orbital involvements in cherubism may develop beyond puberty after stabilization or regression of the lesion of the jaws.